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がんの進展に関与しているとされる線維芽細胞の中の重要な細胞内シグナル伝達系のひとつを、名古屋大学大学院医学系研究科の高橋雅英(たかはし まさひで)教授、浅井直也(あさい なおや)准教授、榎本篤(えのもと あつし)准教授らが解明した。がんの進展には、がん細胞だけでなく、周りの線維芽細胞の活性化が大きな役割を果たしている。その一因となるシグナル伝達を突き止めたもので、がんの治療法開発の新しい標的になるという。名古屋大学循環器内科の室原豊明(むろはら とよあき)教授、山村由美子(やまむら ゆみこ)客員研究員らとの共同研究で、3月2日付の米科学誌キャンサーリサーチに発表した。

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